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Date: 27 July 1980 / 27 July 1980
Heats
Final
| Rank | Name | Nation | Time |
| 1 | Barbara Krause; Caren Metschuck; Ines Diers; Sarina Huelsenbeck { + Carmela Schmidt} | GDR | 3:42.71 |
| 2 | Carina Ljungdahl; Tina Gustafsson; Agneta Mortensson; Agneta Eriksson { + Birgitta Jonsson; Helena Peterson} | SWE | 3:48.93 |
| 3 | Conny van Bentum; Wilma van Velsen; Reggie de Jong; Annelies Maas | NED | 3:49.51 |
| 4 | Sharron Davies; Kaye Lovatt; Jacqueline Willmott; June Croft | GBR | 3:51.71 |
| 5 | Lisa Curry; Karen van de Graaf; Rosemary Brown; Michelle Pearson | AUS | 3:54.16 |
| 6 | Isabel Reuss; Dagmar Erdman; Teresa Rivera; Hellen Plaschinski | MEX | 3:55.41 |
| 7 | Dobrinka Mincheva; Rumiana Dobreva; Ani Kostova; Stoianka Dyngalakova | BUL | 3:56.34 |
| 8 | Natalia Mas; Margarita Armengol; Laura Flaque; Gloria Casado | ESP | 3:58.73 |
| Disqualified | |||
| Heats | |||
| Irina Gerasimova; Natalia Strunnikova; Larisa Tsareva; Olga Klevakina | URS | ||