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Summary
| Rank | Name | Nation | Time |
| 1 | Angelo Taylor | USA | 47.25 |
| 2 | Kerron Clement | USA | 47.98 |
| 3 | Bershawn Jackson | USA | 48.06 |
| 4 | Danny McFarlane | JAM | 48.30 |
| 5 | L.J. van Zyl | RSA | 48.42 |
| 6 | Marek Plawgo | POL | 48.52 |
| 7 | Markino Buckley | JAM | 48.60 |
| 8 | Periklis Iakovakis | GRE | 49.96 |