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Date: 19 August 2010 / 22 August 2010
Heats
Final
| Rank | Name | Nation | Time |
| 1 | Xie Zhenye | CHN | 21.22 |
| 2 | Keisuke Homma | JPN | 21.27 |
| 3 | Patrick Domogala | GER | 21.36 |
| 4 | Brandon Sanders | USA | 21.44 |
| 5 | Jeneko Place | BER | 21.50 |
| 6 | Okeudo Jonathan Nmaju | NGR | 21.52 |
| 7 | Tomasz Kluczynski | POL | 21.56 |
| 8 | Antonio Rodrigues | BRA | 21.60 |
| Final 2 | |||
| 9 | Luca Valbonesi | ITA | 21.98 |
| 10 | Darvin Sandy | TTO | 22.15 |
| 11 | Ousman Gibba | GAM | 22.16 |
| 12 | Mlandvo Shongwe | SWZ | 22.46 |
| 13 | Abdullah Alasiri | KSA | 22.49 |
| Final 3 | |||
| 14 | Ts'Ehla Monethi | LES | 22.14 |
| 15 | Davron Atabaev | TJK | 22.24 |
| 16 | J'Maal Alexander | IVB | 22.73 |
| 17 | Isaac Gbadegesin | CIV | 23.05 |
| Final 4 | |||
| 18 | John Rivan | PNG | 22.12 |
| 19 | Celso Francisco Cossa | MOZ | 22.99 |
| 20 | Antimo-Constantino Oyono Nchama | GEQ | 23.08 |
| 21 | Lonzo Wilkinson | SKN | 23.23 |
| 22 | Jason Leslie | BIZ | 25.43 |
| Did not finish | |||
| Guy-Elphege Anouman | FRA | 21.95 | |
| Siphelo Ngqabaza | RSA | 22.75 | |
| Faisal Jasim Mohamed Mohamed | BRN | 23.19 | |
| Did not start | |||
| Hensley Paulina | AHO | ||