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Date: 23 August 2010
Final
| Rank | Name | Nation | Time |
| 1 | Americas Myasia Jacobs; Tynia Gaither; Rashan Brown; Robin Reynolds |
2:05.62 | |
| 2 | Africa Josephine Omaka; Nkiruka Florence Nwakwe; Izelle Neuhoff; Bukola Abogunloko |
2:06.19 | |
| 3 | Europe Annie Tagoe; Anna Bongiorni; Sonja Mosler; Bianca Razor |
2:07.59 | |
| 4 | Oceania Michelle Jenneke; Monica Brennan; Hazel Bowering-Scott; Jenny Blundell |
2:13.96 | |
| 5 | Asia Wei Liang; Ching-Hsien Liao; Marina Zaiko; Elina Mikhina |
2:15.01 |